Updated Apr 24, 2020

Jennifer Dent

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The WIPO Re:Search consortium was founded in 2011 by the World Intellectual Property Organization (WIPO) in partnership with BVGH and several leading pharmaceutical companies. The aim of the Consortium is to accelerate the development of new drugs, vaccines, and diagnostics for neglected tropical diseases (NTDs), malaria, and tuberculosis by connecting private industry’s assets and resources...

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The WIPO Re:Search consortium was founded in 2011 by the World Intellectual Property Organization (WIPO) in partnership with BVGH and several leading pharmaceutical companies. The aim of the Consortium is to accelerate the development of new drugs, vaccines, and diagnostics for neglected tropical diseases (NTDs), malaria, and tuberculosis by connecting private industry’s assets and resources to qualified academic and nonprofit researchers with product discovery or development ideas.


How does your innovation work?

WIPO Re:Search is a voluntary endeavor open to qualified entities, provided they agree to abide by the WIPO Re:Search Guiding Principles: 1.Members will provide a royalty-free license for any product developed through WIPO Re:Search that is used and sold in the least developed countries (LDCs). 2.Members will consider the issue of access and affordability to these products for all developing countries, including those that do not qualify as LDCs. 3.Members will provide royalty-free licenses for NTD, malaria, and tuberculosis research and development. 4.Intellectual property (IP) asset users will retain ownership of any new IP developed, but are encouraged to make new inventions available to other Members of WIPO Re:Search. An organization can join WIPO Re:Search as a User, Provider, and/or Supporter Member. Provider Members contribute their IP and resources to User Members. User Members utilize these contributed IP and resources in their neglected disease research. Supporter Members support the Consortium’s mission, activities, and objectives. WIPO Re:Search is led jointly by WIPO and BVGH. WIPO is responsible for managing the WIPO Re:Search database, an online database of IP assets that Provider Members have demonstrated a willingness to share; organizing IP workshops for Members; and coordinating the WIPO Re:Search Annual Meeting. BVGH is responsible for recruiting new WIPO Re:Search Members and establishing WIPO Re:Search collaborations. The BVGH team proactively examines Member scientists’ current neglected disease research and proposes novel collaboration opportunities with other Members. Inquiries and requests from researchers are also managed and facilitated by BVGH, who identifies Member organizations able to fulfill these requests, and helps forge mutually beneficial collaborations with clearly-defined roles, responsibilities, and expectations. After a collaboration has been established, BVGH continues to provide partnering support including tracking collaboration progress, maintaining communications, and resolving challenges. Both BVGH and WIPO are responsible for communicating the activities and achievements of WIPO Re:Search.

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Stage 6: Sustained Scale

At its launch, 31 for-profit, nonprofit, academic, and government research organizations belonged to the WIPO Re:Search Consortium. Membership has grown to include 105 Members from 29 countries and six continents. One hundred research collaborations have been established through WIPO Re:Search to date. These collaborations are focused on basic research and drug, vaccine, and diagnostic development for 13 neglected infectious diseases. Seventeen of these collaborations have advanced to the next stage of product development, including ten that are still ongoing.


There are currently 105 for-profit, nonprofit, academic, and government organizations that belong to the WIPO Re:Search consortium: Aberystwyth University Africa Fighting Malaria African Inst. of Biomedical Science and Technology (AiBST) Alnylam Pharmaceuticals Armauer Hansen Research Institute (AHRI) Assoc. of University Technology Managers (AUTM) Bibliotheca Alexandrina Biomedical Research Institute - Biotechnology Industry Organization (BIO) California Institute of Technology Case Western Reserve University Center for Infectious Disease Research Center for World Health & Medicine Central University of Quito-Ecuador Centre Pasteur du Cameroun Cheikh Anta Diop University Council on Health Research and Development (COHRED) Developing World Health Drugs for Neglected Diseases initiative (DNDi) Eisai Emory University Eskitis Institute at Griffiths University European Commission FIND Diagnostics Fundação Oswaldo Cruz (Fiocruz) GALVmed GlaxoSmithKline (GSK) Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Icahn School of Medicine Indian Council for Medical Research Infectious Disease Research Institute (IDRI) Institut Pasteur Institut Pasteur de Tunis Institut Pasteur Korea International Centre for Genetic Engineering and Biotechnology (ICGEB) International Federation of Intellectual Property Attorneys (FICPI) International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) International Hospital Federation (IHF) International Vaccine Institute (IVI) Johnson & Johnson Kenya Agricultural & Livestock Research Organization (KALRO) Kenya Medical Research Institute (KEMRI) Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR) Licensing Executive Society International (LESI) Liverpool School of Tropical Medicine Mahidol University Malaria Consortium Massachusetts General Hospital Massachusetts Institute of Technology (MIT) McGill University McMaster University Medical Research Council—South Africa Medical Research Institute, Alexandria University Medicines for Malaria Venture (MMV) Merck KGaA, Darmstadt, Germany MSD (trade name of Merck & Co., Inc., New Jersey, USA) Murdoch Childrens Research Institute – P, U National Center for Genetic Engineering and Biotechnology (BIOTEC) National Institute of Immunology (India) National Institute of Industrial Property (INPI) National Institute of Parasitic Diseases, China CDC National University of Singapore (NUS) Nigerian Institute of Medical Research Noguchi Memorial Institute for Medical Research Northeastern University Novartis Operation ASHA PATH Pfizer Public Interest Intellectual Property Advisors (PIIPA) Research Institute for Tropical Medicine Sabin Institute Salvensis Sanofi Stanford University Swiss Tropical and Public Health Institute Takeda Tech Transfer Summit Ltd. (TTS) Theodor Bilharz Research Institute Tulane University U.S. National Institutes of Health U.S. Patent and Trademark Office University of Bamako University of Bamenda University of British Columbia University of Buea University of Calgary University of California, Berkeley University of California, San Diego University of California, San Francisco University of Dundee University of Edinburgh University of Ghana University of Ibadan, Nigeria University of Kansas University of Lagos University of Mauritius University of New South Wales University of South Florida University of Vermont University of Washington University of Yaoundé I Walter and Eliza Hall Institute of Medical Research Walter Reed Army Institute of Research (WRAIR) Washington University in St. Louis


Since the Consortium was launched, BVGH has established 100 collaborations. Fifty-nine of the 82 User and/or Provider Member organizations have participated in a collaboration. Seventeen of the collaborations have advanced to the next stage of development, including ten that are still ongoing. The results of these collaborations have been presented by Members at scientific conferences and published in peer-reviewed journals. Examples of these publications include: 1.“Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni”, PLoS Negl. Trop. Dis., 2016. 2.“Evaluation of Non-Instrumented Nucleic Acid Ampli¬cation by Loop-Mediated Isothermal Ampli¬cation (NINA-LAMP) for the Diagnosis of Malaria in Northwest Ethiopia”, Malaria Journal, 2015. 3.“Molecular Testing for Plasmodium falciparum using Serum or Plasma and Comparison with Microscopy and Rapid Diagnostic Testing in Febrile Nigerian Patients”, J. Clin. Microbiol., 2015. 4.“Selamectin is the Avermectin with the Best Potential for Buruli Ulcer Treatment”, PLoS Negl. Trop. Dis., 2015.

Focus Areas:

Health, Infectious & Vector Diseases and Public-Private Partnerships

Health, Infectious & Vector Diseases and Public-Private PartnershipsSEE LESS

Planned Goals and Milestones

During its initial years post-launch, the Consortium focused on expanding the number of Member organizations and establishing a wide variety of research collaborations. WIPO Re:Search will continue to recruit new Member organizations and establish new collaborations. As the organization responsible for these activities, BVGH will take a more targeted, strategic approach to recruiting and partnering. This strategy will include reviewing the current product development pipelines for the neglected tropical diseases, malaria, and tuberculosis; identifying gaps in these pipelines; and establishing research collaborations specifically focused to address these gaps. In the event that none of the current WIPO Re:Search Member organizations have the skills, assets, or capabilities to perform the needed research projects, BVGH will strategically recruit new Member organizations that are able to fulfill these needs. Ten biopharmaceutical companies are Provider Members of WIPO Re:Search. As the number of User Members expands, the need for more company Provider Members with compound libraries, data, and product development expertise grows. BVGH will continue to recruit additional biopharmaceutical and diagnostic companies to participate in WIPO Re:Search and contribute their assets to Members’ neglected infectious disease research and development activities.


BVGH and WIPO are reviewing potential opportunities to leverage the WIPO Re:Search consortium and its Members’ capabilities. These potential opportunities include establishing an open-access research results database where data – both positive and negative – obtained through a WIPO Re:Search collaboration can be deposited; coordinating training/capacity-building opportunities for low- and middle-income country (LMIC) scientists at WIPO Re:Search Member companies and academic institutes; and creating a platform through which small grants can be applied for by and awarded to organizations participating in WIPO Re:Search collaborations.

Milestone

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