The Bubble Box is a kit containing components to set up a low cost version of the Bubble CPAP - a safe and reliable device that reduces the need for mechanical ventilation, and therefore the need for transfer to higher care facilities. The Bubble Box costs approximately 1/150 of the price of CPAP devices in the developing world. The kit contains a durable bottle, marked with appropriate measurements, specialised single limb, open loop medical tubing and adjustable neonatal nasal prongs. These three components can be combined with any existing oxygen supply to provide appropriate respiratory support to a newborn suffering from neonatal asphyxia. In babies with respiratory distress, oxygen is delivered to the baby from the oxygen source, baby inhales and then exhales into the water column in the Bubble CPAP bottle, generating pressure which keeps the lungs open thereby reducing the work of breathing. Suitable for use by medical professionals across the globe, a user can set up the device in 5 minutes. In addition to the materials in the kit, a training and support program is provided to the user. The combination of an ultra-low cost device that does not require electricity and the appropriate support for the healthcare professional users provides an accessible, sustainable solution to address neonatal mortality in Nigerian healthcare centres.